Ephraim Kempton was born on 18 Mar 1620/21. He was educated at Merchant Taylors' School from 1630 to 1634 in London, co. Middlesex, England. He died on 24 Jun 1655 in Scituate, Plymouth Co., Massachusetts. and his estate's inventory was taken on 2 Jul 1655. He was married to Joanna Rawlings on 28 Jan 1645/46 in Scituate, Plymouth Co., Massachusetts.

Joanna Rawlings was born about 1625. She died on 31 Mar 1656 in Scituate, Plymouth Co., Massachusetts. Children were:

i. Joanna Kempton.
ii. Patience Kempton was baptized on 21 Nov 1647 in Scituate, Plymouth Co., Massachusetts. She died on 1 Jul 1648 in Scituate, Plymouth Co., Massachusetts. She was born on 2 Oct 1648.
iii. Ephraim Kempton was baptized on 8 Apr 1649 in Scituate, Plymouth Co., Massachusetts. He was born on 1 Oct 1649. He died bet 1 Jan 1712/13 and 12 Apr 1714 in Salem, Essex Co., Massachusetts. He was a gunsmith in Boston, Suffolk Co., Massachusetts.
iv. Manassah Kempton was baptized on 9 Feb 1650/51 in Scituate, Plymouth Co., Massachusetts. She was born on 1 Jan 1652. She died on 28 Nov 1737 in Southampton, Suffolk Co., New York.
v. Ruth Kempton was baptized on 24 Sep 1654 in Scituate, Plymouth Co., Massachusetts. She died on 16 Oct 1714 in Boston, Suffolk Co., Massachusetts.