| 1630 | |
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| 1630/1 | |
| 1631 | |
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| 1632 | |
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| 1635 | | 23 Apr:
Boston Latin School, the oldest school in America, is founded.BLS tBLS |
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| 1636 | |
| 1648 | |
| | 18 Oct:
The "Shoomakers of Boston" along with the coopers, form the first labor organization in America.jstor IA |
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| 1656 | |
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| 1660 | |
| 1689 | |
| 1690 | |
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| 1704 | |
| 1715 | |
| 1716 | |
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| 1717 | | 27 Feb:
A series of four successive snowstorms create the Great Snow of 1717.NEHS NWS |
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| 1721 | | 26 Jun:
During a smallpox outbreak in Boston, Dr. Zabdiel Boylston begins inoculating patients beginning with his own son.MassMoments CW |
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| 1722 | |
| 1755 | |
| 1760 | | 20 Mar:
A "Great Fire" begins at a tavern in Boston and destroys about 350 homes, shops and warehouses by the time it is over.MassMoments BFHS |
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| 1770 | | 5 Mar:
The Boston Massacre. British troops kill five colonists.LoC NPS |
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| 1773 | |
| 1774 | | 25 Mar:
British Parliament passes the Boston Port Act.SCOnline ABH |
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| 1775 | | 18 Apr:
Paul Revere rides out to warn the colonists that the British troops were on the march.PRH LoC |
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| 1776 | | 24 Jan:
After several months, the cannons captured at Fort Ticonderoga make it to Boston.APC AHC |
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| 1780 | | 4 May:
The American Academy of Arts & Sciences is founded.TiS AAoA&S |
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| | 19 May:
Smoke from forest fires cause The Dark Day of 1780.NEHS HI |
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